SAS-1 is a C2 domain protein critical for centriole integrity in C. elegans.
Centrioles are microtubule-based organelles important for the formation of cilia, flagella and centrosomes.Despite progress in understanding the underlying assembly mechanisms, how centriole integrity is ensured Microcontrollers is incompletely understood, including in sperm cells, where such integrity is particularly critical.We identified C.elega